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Mitochondrial dynamics Regulated changes in mitochondrial shape, connectivity, movement and positioning, including fission, fusion, transport and anchoring

FOXO4 plays a key role in regulating cell cycle control, stress resistance, and apoptosis, while p53 is a central regulator of DNA damage response and cellular aging

Through these mechanisms, the combination of CPZ with rapamycin in vivo has been shown to delay remyelination, and prolong demyelination, a critical requirement for the testing of remyelination-based therapies (Sachs et al., 2014)

Melatonin upregulates nuclear factor erythroid-2 related factor 2 (Nrf2) and mediates mitophagy to protect against early brain injury after subarachnoid hemorrhage

(2022) demonstrated that MenSCs significantly enhanced survival in mice while reducing the serum levels of liver injury markers (AST, ALT, ALP, DBIL)