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Description
Nature 1995, 378: 419-419

Rahman, I., Li, X.Y., Donaldson, K., Harrison, D.J

Further mechanistic studies showed that ROS and lipofuscin levels, A aggregation, and toxicity were reduced after p -HBA treatment, suggesting that p -HBA ameliorated A-induced toxicity by enhancing antioxidant and anti-aging activity and inhibiting A aggregation

Gray MS, Singleton WS

This dual mechanism is what makes tirzepatide more effective than single-agonist medications
