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26 If there is a problem eluting the protein from the glutathione Sepharose column, try decreasing the flow rate and increasing the volume of elution buffer that is used

Unfortunately, data on the efficacy of these techniques is lacking and many of these treatments have undesirable side effects

Peripheral neuropathy applications including diabetic neuropathy, chemotherapy-induced neuropathy, and traumatic nerve injuries represent potential indications based on demonstrated nerve regeneration enhancement in animal models

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This results in the upregulation of inflammatory molecules such as IL-6 and TNF-, which promote chronic inflammation and further enhance the SASP