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3.1.1 Topoisomerase inhibitors Topoisomerase inhibitors are a class of anticancer drugs whose mechanism of action is based on blocking topoisomerase enzymes from re-ligating the DNA strands after supercoiling, thus preventing DNA replication [61]

In cases of long-standing or severe deficiency, nerve damage may be partially irreversible, highlighting the importance of early detection and treatment

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So long as no more ethanol is added, the person drinking any of the 3 described alcohol drinks will be ingesting approximately the identical amount of poison (alcohol) into his or her body