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Induction of mitochondrial biogenesis protects against acetaminophen hepatotoxicity

Exploiting related enzymes that generate these harmful metabolites may be a promising strategy

Vitamin D is a fat-soluble vitamin that is stored in the liver and fatty tissues of the body

Primers consisted of the following sequences: F_GPX2_OE: 5- CTTTAAAGGAACCAATTCAGccaccATGGCTTTCATTGCCAAGTCCTTC 3, R_GPX2_OE: 5- AAGCTGGGTCTAGATATCTTActtatcgtcgtcatccttgtaatcacgTATGGCAACTTTAAGGA 3

TAD is a phosphodiesterase 5 inhibitor that exerts cardioprotective effects against ischemia/reperfusion (I/R) injury in diabetic mice, whereas HCQ is an antimalarial and anti-inflammatory drug that reduces hyperglycemia in diabetic patients
