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This suggests that stimulation requires either a FAT10-bound, partially open conformation of NUB1 with an exposed UBL domain or substrate engagement and degradation, which shifts the proteasome from nonprocessing to processing states with an open 20S peptidase gate

Kedziora-Kornatowska K, Czuczejko J, Pawluk H, Kornatowski T, Motyl J, Szadujkis-Szadurski L, Szewczyk-Golec K, Kedziora J

Beyond modulating lipid profiles, some probiotics also assist in regulating blood pressure (415)

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Dong S, Lu Y, Peng G, Li J, Li W, Li M, Wang H, Liu L, Zhao Q
