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For instance, in transgenic AD animal models, Lipid Nanoparticles have been employed to deliver siRNA that targets the amyloid precursor protein (APP) or presenilin 1 (PSEN1)

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1 Introduction Pancreatitis is the main inflammatory disease of the gastrointestinal tract ( CP is characterized by persistent inflammation of the pancreas with progressive loss of endocrine and exocrine compartments due to atrophic and/or fibrotic tissue replacement ( In this review, we discuss the role of various immune cell populations and pancreatic stellate cell populations in CP, as well as current advances in targeted therapies based on different cell populations