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E., Liu, F., Cao, Q., Swago, S., Jacobs, P

Choosing between IV and oral glutathione requires weighing bioavailability against safety, cost, and convenience factors

doi: 10.1016/S0083-6729(06)77007-8 57 ChabotFCaronALaplanteMSt-PierreDH

For T cells, triptolide is reported to overturn T cell suppression, particularly CD4 + T cells subset in glioma (T98G) cells under IFN- treatment, while significantly decreases the proportion of Tregs in the spleen and axillary lymph nodes of melanoma (B16-F10) bearing mice, thereby impairing their suppressive function through the down-regulation of Foxp3, IL-10, and transforming growth factor in both protein and mRNA levels [974, 975]