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Acknowledgements We thank the Laboratory of Basic Medical Sciences of Qilu Hospital for its help
10.1021/acs.jafc.6b05559
Although the nanoparticle drug delivery system was not initially designed for LDL-receptor-mediated brain targeting, it was later found that apolipoprotein E would be absorbed on the polysorbate 80 coated nanoparticles upon incubation of the nanoparticles with human plasma resulting in LDL-receptor mediated BBB crossing
doi: 10.1159/000486115
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