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This is one reason it's considered a "conditionally essential" nutrient: Your body produces it, but if it doesn't produce enough, your health can be seriously impacted

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However, the evidence for chronic fatigue syndrome/myalgic encephalomyelitis (ME/CFS) remains limited, and NICE guideline NG206 does not recommend supplements as a treatment for ME/CFS

Inositol for the prevention of gestational diabetes: a systematic review and meta-analysis of randomized controlled trials
doi: 10.1016/j.plipres.2009.08.004 31 KoethR.CulleyM.WangZ.NemetI.KirsopJ.OrgE.et al