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10.1124/jpet.104.071860 147 StorckT.SchulteS.HofmannK.StoffelW

These tests not only measure B12 levels but also help identify potential underlying causes of deficiency

If glucose is available in excess, aldose reductase convert glucose into sorbitol through the polyol pathway [188]
Neuropharmacology 93: 134145, 2015

However, data on PA concentrations in the brain remain limited