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Clinical evidence and therapeutic dosing demonstrate different optimal applications and protocols

It initiates the Nrf2 pathway, a critical regulatory pathway in cellular antioxidant defence, leading to the upregulation of various antioxidant genes [136]

Incorporating anti-inflammatory agents like dexamethasone into LNPs can mitigate inflammation while maintaining therapeutic effectiveness

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Adverse effects: Orlistat-associated to liver failure Orlistat, a drug inhibiting pancreatic lipase and aimed at aiding weight loss, has been linked to severe liver-related side effects, including the formation of gallstones, liver inflammation with bile obstruction, and acute liver failure, as highlighted in various studies [5, 42, 66,67,68,69]