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SAMe is the primary methyl donor in the body, while methionine is an essential amino acid that is converted to SAMe in the body

Won W, Choi HJ, Yoo JY, Kim D, Kim TY, Ju Y et al (2022) Inhibiting peripheral and central MAO-B ameliorates joint inflammation and cognitive impairment in rheumatoid arthritis

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Natural antioxidants are being explored as preventive measures

1 Life Extension Mega L-Ergothioneine also provides Vitamin C, a well-known antioxidant that works synergistically with L-Ergothioneine to protect cells from oxidative stress, support immune function, and promote overall cellular health