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HIF-1 regulates the cell viability in radioiodine-resistant papillary thyroid carcinoma cells induced by hypoxia through PKM2/NF-B signaling pathway
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To our knowledge, only one study reported a potential link between type I IFN and HIF-1, showing ISG15 capacity to reduce HIF-1 protein levels through proteasome induced degradation without affecting mRNA levels 42
