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In contrast, males seem more susceptible in developed nations, which indicates a possible genetic and lifestyle role in development of the disease

Interestingly, GPx3 was identified as the sole protein with the most significant reduction in signal for children affected with konzo, a finding that was further validated using ELISA as a secondary method of confirmation

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Dietary SOD protects against light-induced retinal oxidative stress in young senescence accelerated mice, P.Sicard, Invest Ophthalmol Vis Sci 2006;47: E-Abstract 2089

The hypermethylated APP gene, in particular, stands out for AD prognosis (53)