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In December 2007, after Phase 3 clinical trials Takeda Pharmaceuticals submitted alogliptin for approval

Exosomes from adipose-derived mesenchymal stem cells (ADSC-Exos) can effectively improve the neurobehavioral function of mice after I/R

Clinical investigation to support new uses generally requires an Investigational New Drug (IND) application with appropriate chemistry, manufacturing, and controls, nonclinical safety, and human data

Neutrophils and inflammatory resolution in the mucosa

In conditions such as OSAHS, CIH typically leads to a suppression of the stress reflex, indicating that estrogen may also ameliorate SNA in OSAHS through this pathway
