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In addition to the increased levels of mtDNA damage, we observed an increase in the levels of 4-hydroxyalkenals (4-HNEs) in the brain (Figure 2), which are markers of lipid peroxidation and thus also serve as indicators of oxidative stress [39]

Kuohung W, Hornstein MD

Jackson, S

The state of ketosis achieved by the diet can be referred to as nutritional ketosis, which in itself shows a therapeutic potential

Coupled with the limited bioavailability of 10% of orally-supplemented acetylcarnitine, the administration of 2 g acetylcarnitine (10 mmoles) and its incorporation in the TCA cycle would give rise to 12 mmoles ATP per day