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R., Yokote, K., Tanaka, T., & Prives, C
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Adam D (2019) Core Concept: emerging science of chronotherapy offers big opportunities to optimize drug delivery
IKK activation could phosphorylate NF-B inhibitors, leading to their degradation by the proteasome, which then activates and releases NF-B complexes into the nucleus to trigger the expression of target genes involved in cell proliferation and apoptosis, initiating downstream signaling pathways [108]
