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The peptide exhibits the sequence SDKPDMAEI EKFDKSKLKK TETQEKNPLP SKETIEQEKQ AGES with an acetylated serine residue at the N-terminus and an isoelectric point of 5.1

Dissecting the extent of oxidation and reduction of disulfides is an ongoing challenge due, in part, to the facility of thiol/disulfide exchange reactions

& Gorzelnik, T

Cloning of the human glycine transportertype 1: Molecular and pharmacological characterization of novel isoform variants and chromosomal localization of the gene in thehuman and mouse genomes

The most common form of SPIGFD is known as Laron syndrome and results from a mutation to the GHR gene, rendering the affected individual insensitive to GH