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USP15 negatively regulates Nrf2 through deubiquitination of Keap1
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Nat Rev Clin Oncol
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The colonic lining primarily absorbs water and electrolytes, and introducing coffee repeatedly can disrupt the delicate balance of the intestinal microbiome and damage protective mucosal barriers
Thus, the main analytical sample included 2574 participants (2363 from NESDA baseline and 211 siblings) with data on MDD diagnostic status, overall depression severity, and depressive symptoms profiles and at least one of the investigated metabolites
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