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The B12 drops benefits start with skipping this problem entirely

Chloramphenicol, though rarely used in modern practice, can antagonize the hematologic response to vitamin B12 in patients with megaloblastic anemia

Side effects to Vitamin B12 are SO rare that they cannot be estimated from current data (in other words, less than 1 in 10'000)

Nat Med (1):9

Preclinical studies indicate potential roles in: Supporting healthy fat metabolism and reduction of adipogenesis Improving insulin sensitivity in metabolic research models Enhancing NAD+ salvage pathway efficiency Exploring effects on energy homeostasis and longevity pathways These findings remain preliminary and confined to laboratory and animal models