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IL-1 stimulates NF-B with subsequent increased production of inflammatory cytokines [107], including macrophage migration inhibitory factor (MIF) in endometrial stromal cells [108] and TNF- in the immortalized epithelial (12Z) cell line [109]
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CCL20 mediates lipopolysaccharide induced liver injury and is a potential driver of inflammation and fibrosis in alcoholic hepatitis
Take two capsules daily, first thing in the morning, preferably on an empty stomach
A clear link between disease severity, hyper-inflammation, and major comorbidities, including hypertension, diabetes, and CVD has been established
