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Shanghai Young University Teacher Training and Support Program [Grant Number: 10110N255125-A07]

Rodrigues DGB, Coelho D de M, Sitta , Jacques CED, Hauschild T, Manfredini V, Bakkali A, Struys EA, Jakobs C, Wajner M (2017) Experimental evidence of oxidative stress in patients with l-2-hydroxyglutaric aciduria and that l-carnitine attenuates in vitro DNA damage caused by d-2- hydroxyglutaric and l-2-hydroxyglutaric acids

Int J Cancer Res

The gene family members share multiple conserved motifs, including the Gly-x-Ser-x-Gly lipase consensus sequence, a catalytic Ser-Asp-His triad, cysteine residues responsible for intramolecular disulfide bond formation, and lipid binding surface loops, including the lid domain and the 9 loop ( Fig

During a final 30-minute all-out effort, the carnitine users sustained a 35% greater workload than the control group who did not supplement carnitine