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Previously unreported effects of RSL3, such as degradation of mTOR signaling pathway protein, p70S6K, and reduction of p-NPM1 levels were identified in the present study and warrant further investigation

Statements Author contributions EK: Conceptualization, Data curation, Formal Analysis, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing original draft, Writing review and editing

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10.1073/pnas.85.17.6465 120 RichterF.SubramaniamS

Reported effects include mild headache early in a cycle, sleep changes, mild gastrointestinal effects with oral use, and injection-site redness with subcutaneous use