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2002 May;75(5):789808

This direct delivery method theoretically provides higher bioavailability, meaning more of the active compound reaches target tissues

17 , e3000284 (2019)
Vitamin C: antioxidant or pro-oxidant in vivo
155,156 PI3Ks are members of a family of lipid kinases that phosphorylate the 3-hydroxyl group of phosphatidylinositol (PIP) and PIP2 at the third position, to form PIP2 and PIP3, which activate downstream kinases such as AKT and glycogen synthase kinase 3 (GSK-3), which during ischemia-reperfusion injury results in reduced cell death and infarct size
