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The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex

However, these compounds have been confirmed to have significant neuroprotective and preventive activity in OIPN preclinical and clinical data [186, 187]

Among the EMT-related E-cadherin protein level in the PCDHGA9 knockdown group was significantly reduced, while the expression of N-cadherin, imentin, and Snail proteins was significantly increased, and the PCDHGA9 overexpression group showed the opposite trend (Mei et al., 2024)

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It also can enhance GLP-1 levels, alleviate endoplasmic reticulum (ER) stress, improve peripheral insulin sensitivity, and increase skeletal muscle mass ( In terms of inhibiting LPS induced inflammatory factors, L