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Somewhat surprisingly, both drugs' side effect profiles were similar

Studies have shown that after treatment with modified Gegen Qinlian decoction and its metabolites baicalein, berberine and glycyrrhizic acid, the activity of diamine oxidase and D-lactic acid in serum significantly decreased, and the levels of ZO-1, occludin, and claudin 1 in colon tissues increased, suggesting that the therapeutic effect of modified Gegen Qinlian decoction may be related to a reduction in intestinal permeability [94]

Rotating sites systematically helps prevent accumulation of local reactions

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