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We have previously reported on an oxaliplatin-based platinum(IV) complex featuring a maleimide moiety which has shown high antitumor activity in vivo 14

Approximately 70% of GPX3, the predominant form in the basolateral compartment of kidney cells [15], is secreted by the basolateral membrane of proximal convoluted tubule cells [16]

Additionally, GSTM2 -overexpressing mice showed mild LD accumulation in the first 3 weeks (Fig