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Acknowledgments This study received financial support from Fundao de Amparo a Pesquisa de Gois (FAPEG), Coordenao de Aperfeioamento de Pessoal de Nvel Superior (CAPES), and Conselho Nacional do Desenvolvimento Cientfico e Tecnolgico (CNPq)
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SIRT1, a target in the inflammatory response of articular chondrocytes is activated by curcumin, which protects chondrocytes by inhibiting MMP-13 and NF-B expression

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