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Respiratory syncytial virus co-opts host mitochondrial function to favour infectious virus production

Precisely through its regulatory role (e.g., GSH, GST), Nrf2 counteracts 3-NP-induced enhanced OS (Vasconcelos et al

S.Van de WaterJ

Drugs that target intrinsic metabolic vulnerabilities (e.g., GLUT1 inhibitors, PDK4 inhibitors, or glutaminase inhibitors) predispose cancer cells to death, which is triggered by decreased nicotinamide adenine dinucleotide phosphate generation or increased reactive oxygen species accumulation
