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Subgroup analyses should be performed for specific populations, such as those with treatment-resistant depression, psychotic features, mixed features, anxiety symptoms, or atypical depression

The loss of function of E-cadherin is associated with cancer progression by enhancing proliferation, invasion, and metastasis, and the shift toward increased expression of N-cadherin contributes to the disruption of intercellular junctions and initiates the process of epithelialmesenchymal transition (Jiang et al

wrinkles begin to appear because of the decline in collagen and elastin fibers in the dermal layer [2, 10, 14, 20]

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512 However, the side effects of CYP inhibitors can not be ignored because of the important effects of CYP enzyme on drug metabolism and their double-edged sword on CVD and cancer treatment