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The most comprehensive study, published in BioMed Research International (2021), found that 5-amino-1MQ treatment "reverses diet-induced obesity and related T2D" in obese mice
Although dietary fiber has been associated with microbiome changes 75 , this is unlikely to account for the microbiome changes observed herein since fiber content was the same across diets
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Based on these results, we monitored changes in intracellular 1-MNA in response to 24 h treatment with varied 5-amino-1MQ concentrations
