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Description
Mitochondrial dysfunction in perimenopausal mood disorders is often accompanied by oxidative stress and neuronal injury

Conversely, decreased GH/IGF-1 signaling has also been shown to extend longevity in a wide variety of species such as worms, fruit flies, mice, and yeast (468), thus raising the question of whether decreased activity of the GH/IGF-1 axis might be beneficial for human longevity

Cell 155 : 778-92

Billi, A

Impact of the Alzheimer's Disease Neuroimaging Initiative, 2004 to 2014
