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Biom J 50 , 346363, (2008)

A specific mechanism by which glutathione thiol and glutathione disulfide operate to this aim is the reversible thiol(ate)-exchange mechanism, through which an excess of glutathione thiol regulates in an inhibitory sense the biological pathways which produce reducing cofactors or conditions by binding to sensing, conformation-determining disulfide bonds of proteins in a process termed reversible protein glutathionylation [134]

This includes diagnoses like pernicious anemia, dietary folate deficiency, or other diseases classified under B vitamin deficiencies

Mittar, S