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The impairment of Mitochondrial Quality Control and resulting mitochondrial dysfunction are strongly linked to age-related diseases and respiratory disorders, including asthma, COPD, idiopathic pulmonary fibrosis and lung cancer (Sharma et al., 2021

Current research suggests that a varied diet including sulfur-rich vegetables, fresh produce, and quality protein sources may help provide dietary glutathione and supporting nutrients

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Bacterial GST genes are often located within gene clusters, which suggests an important role of GST proteins in metabolic degradation and detoxification pathways (Marsh et al., 2008)

Regarding the oxidative biomarker (MDA), animal groups treated with PFD (standard treatment) and VCN demonstrated a statistically significant reduction in the level of MDA compared to the induced group with p-value (P = 0.05 and P = 0.0001), respectively, and VCN-treated animals showed a better reduction in MDA compared to standard treatment (P = 0.005) as demonstrated in [Fig