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In addition, a further study showed STAT3 upregulation was associated with GH hypersecretion in pituitary somatotroph adenomas (73)

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Disturbances in calciumphosphate metabolism, acidbase balance, and vitamin D synthesis are common in chronic kidney disease and have been linked to altered synaptic function, excitotoxicity, and reduced dopaminergic neuronal resilience [33]

Absorbance was measured at 490nm at a GloMax 96 well plate reader (Promega)

The sterol ligands in these GPCRs insert into the transmembrane domain perpendicularly to the membrane, in contrast to the binding pose of DHF, which is almost parallel to the membrane