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Finally, a critical layer of defense exists in the meticulous regulation of transition metals, particularly iron

Bhowmick S, DMello V, Caruso D, et al
MEDI PEEL Bio-Intense Glutathione Emulsion, 30

For example, mitochondrial ROS (mtROS) directly sulfenylated uncoupling protein 1 (UCP1) in brown adipose tissue, leading to promoted thermogenesis, energy expenditure and consequently loss of weight [86]
doi: 10.1039/c3nr00357d