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Description
Sepiapterin reductase deficiency: clinical presentation and evaluation of long-term therapy

Compared with subjects with normal renal function, the geometric mean plasma C max increased by 41% following a lesinurad 200 mg dose in subjects with mild impairment

Guoqiang Cao, MD1,3

You might have poor immunity, white marks on your nails, slow healing of wounds, and a very low appetite

Patients in the dose reduction group were switched to either reduced dose (37.5mg daily, n = 20) or alternate-day dosing (75mg every other day, n = 34) based on clinical assessment
