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Second, we included RCTs that examined complementary endpoints, providing a comprehensive review of this topic

Multiple reproductive abnormalities, including decreased oocyte maturation, disturbed follicular development and ovulation, heightened rates of follicular atresia, and eventually infertility, are caused by conditional deletion of Dicer1 exclusively in mammalian follicular granulosa cells (GCs) [87,88,89]

36 Yet, these compensatory mechanisms are often inadequate during high-speed or unpredictable movements, leading to a heightened risk of instability

Therefore, the antioxidant defence systems play a vital role in maintaining an optimal redox balance in melanocytes by quenching ROS and protecting against oxidative stress, excessive melanogenesis and photo-damaged skin