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Amelioration of hepatic steatosis in mice through bacteroides uniformis CBA7346-mediated regulation of high-fat diet-induced insulin resistance and Lipogenesis

These parameters act through distinct yet interconnected pathways to disrupt the delicate orchestration of the circadian system, with downstream consequences for reproductive endocrinology (Figure 3)

For instance, PhiKan083 and PK7088 specifically target the mutant p53 Y220C protein by stabilising its structure, thereby increasing the levels of p53 Y220C proteins with WT conformation and activity [209, 210]

Preferential associations between co-regulated genes reveal a transcriptional interactome in erythroid cells