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Based on the double action of OHP dosage in neuropathy and chemotherapeutic effect, some chemosensitizers such as cerulenin may enhance the therapeutic effects of OHP, and thus lower the OHP-induced neuropathy [204]

It requires a physician who understands your unique health picture

This oxidative damage can promote the release of autoantigens and disrupt immune tolerance, contributing to the initiation of autoimmune responses against the thyroid

Cai QY, Zhou ZJ, Luo R, Gan J, Li SP, Mu DZ, et al

To overcome these translational barriers and navigate the narrow therapeutic window, future clinical strategies must pivot towards precision medicine, focusing on: (1) Patient Stratification and Personalized Therapy: Utilizing iron-sensitive MRI techniques like QSM and CSF iron-related biomarkers for patient stratification to enable personalized, tailored, and adjustable chelation regimens that maximize net benefit and minimize the risk of excessive iron removal [123, 133]