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HIF-1 upregulates glycolytic enzyme genes [such as HK2, PFKFB3 and lactate dehydrogenase (LDH)] and promotes GLUT1 synthesis

Absorption data on sublingual delivery is thinner than for liposomal, and results vary

To ensure consistency across treatments, the final DMSO concentration was standardized and maintained constant for all experimental groups, including the vehicle controls

While one may think injecting in the area around the belly button is a good idea given that it is easily accessible and provides a good amount of subcutaneous tissue, it should be avoided as this area is more sensitive and prone to cause discomfort

Biological females have significantly lower levels of gastric ADH activity than males