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Extracellular matrix production by nucleus pulposus and bone marrow stem cells in response to altered oxygen and glucose microenvironments

Wickstrm, M

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Evidence suggests that RGD enhances cell attachment and spreading of osteoblasts onto scaffolds and graft material [140, 141, 159, 188] whilst increasing cellular proliferation and the expression of ALP, Runx2, osteocalcin, osteopontin and bone sialoprotein [141, 142, 146, 190, 191]

This can occur due to loss of appetite, digestive issues, and muscle weakness, which are common side effects of B12 deficiency