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Although many studies support the positive correlation between metformin use and vitamin B12 deficiency, there is still uncertainty about whether metformin causes anemia and whether this is triggered by B12 deficiency or not in metformin-treated T2DM patients[51,52]

Helicobacter pylori infection and antioxidants can modulate the genotoxic effects of heterocyclic amines in gastric mucosa cells

If you have a sensitive stomach, you can take it with a light meal

To put it in plainer terms, they propose that the high levels of oxidative stress and inability of the immune cells to produce proper amounts of energy could explain everything