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A persons individual disease presentation all of the signs and symptoms of the disorder is influenced by the specific cause, type, and other factors

J Am Chem Soc 133(31):1222912237 Ma LS, Jiang CY, Cui M, Lu R, Liu SS, Zheng BB et al (2013) Fluopsin C induces oncosis of human breast adenocarcinoma cells

The role of insular neurometabolites in gastrointestinal symptoms, particularly pain, in Crohns disease patients, however, is not well-understood, highlighting the need for further investigation

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Indeed, increased mitochondrial oxidant stress in human SNc neurons has been shown to initiate a dopamine- and iron-dependent toxic cascade, leading to lysosomal dysfunction and -synuclein accumulation in the presence of a PD-associated DJ-1 mutationthus establishing a causal link among key pathological features of PD [154,155]