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Efferently, the VN regulates bronchial smooth muscle primarily through parasympathetic cholinergic pathways, where ACh release causes bronchoconstriction via muscarinic receptors (Fryer and Jacoby 1998)

Recently, tryptophan metabolism was found to protect against in vitro T-cell mediated -cell killing through PD-L1 agonism (Rachdi et al., 2023)

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Heat inactivation altered peptide profiles but maintained or even increased peptide content, while fermentation reduced lactose and increased galactose and organic acids, indicating proteolysis and saccharolytic activity ( The dairy industry is currently focusing on developing innovative functional products by incorporating probiotic bacteria into fermented milk ( Lactobacilli and Bifidobacteria (62)