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*Correspondence: Bengt Mannervik, [email protected] This article was submitted to Cellular Biochemistry, a section of the journal Frontiers in Molecular Biosciences Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

A better understanding of ferroptosis in the TME could illuminate novel aspects of this process and promote the development of targeted therapies

Activated protein C (APC) is an anticoagulant serine protease derived from PC after proteolytic activation by thrombin 1