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Loading phase (deficiency): 1000 mcg IM or subQ daily or every other day for 1 to 2 weeks Maintenance: 1000 mcg monthly is a standard maintenance dose for conditions like pernicious anemia Wellness protocols: may use lower doses weekly, though this is less established clinically In ml: cyanocobalamin is typically supplied at 1000 mcg/ml, so a 1000 mcg dose equals 1 ml

Avoid administration immediately after meals, particularly high-carbohydrate meals

Adipose tissue deficiency, glucose intolerance, and increased atherosclerosis result from mutation in the mouse fatty liver dystrophy ( fld ) gene

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