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Estrogen receptor ligand therapy activates PI3K/Akt/mTOR signaling in oligodendrocytes and promotes remyelination in a mouse model of multiple sclerosis
(2019) 98:e16114
The compound remains available through research chemical suppliers and peptide vendors for research purposes
While these findings are encouraging, further studies are needed to evaluate the long-term safety, reproducibility and translational applicability across additional models and treatment paradigms
These reports suggest that lowering glutathione levels can alter the presynaptic mechanisms involved in neurotransmitter release
