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Loss of the glycine N-methyltransferase gene leads to steatosis and hepatocellular carcinoma in mice

Ebselen was found to increase the expression of GPX1 in SGNs after peroxynitrite damage, which is consistent with the reports that ebselen can increase the expression of GPX1 in cochlea after electrical stimulation ( gpx1 / mice leads to the aggravated SGN injury (cell loss and apoptosis) induced by peroxynitrite, although it might cause no effect on SGN development as SGNs presented normal morphology and cell number in gpx1 -deficient mice

Proteome Res 7(10):455765 [DOI] [PubMed] [Google Scholar] 98.Philip M, Funkhouser SA, Chiu EY, Phelps SR, Delrow JJ, et al

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